Acute Normovolemic Hemodilution (ANH) has a weird-sounding name, but it’s a totally logical way to reduce red cell transfusions. Steve Frank shows us why.
NOTE: Continuing Education credit for this episode has expired. See below for details.

Dr. Steve Frank
He USES It!
Dr. Steve Frank and his colleagues in the Bloodless Medicine Program at Johns Hopkins believe ANH is an underutilized strategy. He joins me today to share the details of how ANH works, and whether other facilities can implement it as a part of their overall Patient Blood Management Program.

Dr. Steve Frank
He USES It!
Dr. Steve Frank and his colleagues in the Bloodless Medicine Program at Johns Hopkins believe ANH is an underutilized strategy. He joins me today to share the details of how ANH works, and whether other facilities can implement it as a part of their overall Patient Blood Management Program.
About My Guest:
Dr. Steve Frank is a Professor in the Department of Anesthesiology and Critical Care Medicine at the Johns Hopkins Medical Institutions, where he specializes in anesthesia for vascular, thoracic, and transplant cases. He serves as Medical Director for the Johns Hopkins Health System Blood Management Program and he also directs the Center for Bloodless Medicine and Surgery, a program for patients who wish to avoid transfusion.
Dr. Frank’s recent work relates to clinical studies in the area of collection and analysis of transfusion data from electronic medical records and methods for using such data to improve practice. He is currently on the Editorial Board of the journal TRANSFUSION, and he has served on the Board of Directors for AABB and SABM. He is also Chair of the Committee on Patient Blood Management for the American Society of Anesthesiologists.
Continuing Education Expired
This podcast episode offered continuing education credit for two years from its release date, but is no longer eligible for such credit.
There are currently no episodes of Blood Bank Guy Essentials eligible for continuing education credit, but check back soon!
DISCLAIMER: The opinions expressed on this episode are those of my guest and I alone, and do not reflect those of the organizations with which either of us is affiliated. Neither Dr. Frank nor I have any relevant financial disclosures.
Further Reading:
- Editorial by Dr. Frank and his group summarizing major issues in ANH: Grant MC, Resar LMS, and Frank SM. The Efficacy and Utility of Acute Normovolemic Hemodilution. Anesth Analg 2015;121(6):1412-1414.
Thanks to:
- Dr. Daniela Hermelin, Managing Editor; Follow Daniela on Twitter for fantastic #blooducation!
- Naomi Suguitan, BBGuy Assistant
Music Credit
Music for this episode includes “Cuando te invade el temor” and “Reflejo,” both by Mar Virtual via the Free Music Archive. Click the image below for permissions and license details.













Very interesting! If I’ve got this right, a major advantage of ANH over cell saver is that we’re replacing whole blood with whole blood whereas with cell saver we’re only replacing the red cells. As a result we avoid coagulopathies associated with loss of plasma and platelets.
For patients treated with cell saver, is there a returned volume of blood that once exceeded should prompt us to suspect impending dilutional coagulopathy?
Thanks!
Great discussion! Would you be able to advise on which collection bags you are using? We are having trouble finding bags for ANH collections.
Thanks !
Is sickle cell or thallasemia patients eligible for ANH?