Glossary: Permanent Deferral

Glossary Permanent Deferral A designation applied to a blood donor who, for one or more of a variety of reasons, will never be allowed to donate blood for someone else. This term and “indefinite deferral” are often confused because they seem so similar...

Glossary: IgG

Glossary IgG IgG (“Immunoglobulin G”) is the most abundant antibody in circulation. It is composed of a single antibody molecule that has two antigen binding sites (think of them as “arms”). IgG is traditionally illustrated in a simple fashion...

Glossary: Pathogen Reduction

Glossary Pathogen Reduction Pathogen reduction is a post-collection blood product manipulation process used for many years in Europe but only relatively recently approved in the United States. A substance is added to platelet and plasma products (not yet red cell...

Glossary: Autoadsorption

Glossary Autoadsorption Read the “Adsorption” definition first, if you have not already done so. Autoadsorption is an advanced blood banking technique that is most often useful in the workup of warm autoantibodies. Usually, warm autoantibodies react very...

Glossary: DTT

Glossary DTT DTT (Dithiothreitol) is a “thiol reagent” that dissolves disulfide bonds between cysteine amino acids, potentially affecting both red cell antigens and antibodies. Other, less commonly used examples of thiol reagents are 2-mercaptoethanol...

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