Glossary: Directed Donation

Glossary Directed Donation A “directed” blood donation occurs when a patient gets the opportunity to choose their blood donor! In general, a physician requests in writing that a particular person or persons donate blood specifically for a particular...

Glossary: G Antigen

Glossary G Antigen G is a combination antigen in the Rh Blood Group System found on red cells containing either D or C antigens. Given the high frequency of D antigen expression (85% of whites, 92% of blacks, 99% of asians), it shouldn’t be surprising that the...

Glossary: H Gene

Glossary H Gene The H gene encodes an enzyme that is required in the expression of the H antigen on the surface of red blood cells. Translation of the active allele, H, of the FUT1 gene results in formation of the enzyme known as α-1,2-fucosyltransferase (H is...

Glossary: IgM

Glossary IgM IgM (“Immunoglobulin M”) is the second or third most abundant antibody in circulation (after IgG and often, IgA). This antibody is composed of five individual antibody “monomers” bound together by disulfide bonds. Since each...

Glossary: Para-Bombay Phenotype

Glossary Para-Bombay Phenotype This rare ABO-related phenotype is described as being an “H-deficient secretor.” Those with Para-Bombay cannot make H antigen on their red blood cells (and can’t make RBC-bound A or B antigen), but unlike those with the...

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