by Joe Chaffin | Mar 8, 2016
Glossary Blood Group System A blood group system is a group of blood group antigens typically inherited from one gene (but occasionally more than one). The ISBT has identified 36 blood group systems. While most blood group systems contain antigens that have similar...
by Joe Chaffin | Mar 22, 2016
Glossary Thrombotic Thrombocytopenic Purpura (TTP) TTP is a form of Thrombotic Microangiopathy (TMA) associated with severe deficiencies of an enzyme called ADAMTS13 (say it like this: “Adam Tee Ess 13”). This enzyme is responsible for the trimming of von...
by Joe Chaffin | Mar 21, 2016
Glossary Massive Transfusion Defined loosely as the rapid administration of a volume of red blood cells roughly equivalent to a “normal” person’s RBC volume. The most common definition is the receipt of 10 units of RBCs within 24 hours, but...
by Joe Chaffin | Jun 6, 2016 | BBGuy Podcast, Immunohematology |
Drugs that lead to immune red cell hemolysis can be super-sneaky and present as unexplained hemolysis! Pat Arndt outlines just how to “sleuth” out these challenging cases! Patricia Arndt, MT(ASCP)SBB from American Red Cross Southern California joins Dr....
by Joe Chaffin | Apr 10, 2017 | BBGuy Podcast, Transfusion Complications |
Transfusing patients with sickle cell disease (SCD) is a big deal, for many reasons. Eric Gehrie guides us through those challenges, especially alloimmunization (making antibodies against red cell antigens). History Lesson: Around 1910, Dr. James Herrick discovered...