by Joe Chaffin | Mar 11, 2016
Glossary Double Dose A somewhat misused term that simply refers to the formation of a red blood cell antigen from the action of two identical alleles (i.e., the person is genetically homozygous for that allele). This is further outlined in the discussion on the Dosage...
by Joe Chaffin | Mar 11, 2016
Glossary Dosage Effect A significant difference in antibody reaction strength depending on the quantity of the target antigen present on a target red blood cell. This is easiest to do with an example. Let’s look at the Kidd (“Jk”) blood group system....
by Joe Chaffin | Mar 12, 2016
Glossary Final Rule Every so often, the U.S. FDA comes out with a new set of requirements for a particular aspect of blood collection and/or processing. These requirements are entered into the Code of Federal Regulations (CFR), and become federal law (FDA does not do...
by Joe Chaffin | Mar 11, 2016
Glossary Direct Exclusion In historical paternity testing, a direct exclusion occurred when a child expressed an antigen that he could not have inherited from the potential father or mother. An example: A group O man is the possible father of a child who is blood...
by Joe Chaffin | Mar 12, 2016
Glossary Fresh Frozen Plasma Fresh Frozen Plasma (FFP) is a blood product most commonly made by separating plasma from whole blood collection and placing it in freezing conditions (-18C or less) within 8 hours of collection. FFP is also made from apheresis...
