by Joe Chaffin | Mar 9, 2016
Glossary Chemiluminescent Immunoassay Abbreviated “ChLIA,” this is a testing method used in blood donor infectious disease screening. ChLIA is very similar in concept to enzyme immunoassay (EIA) in both bind a substance (antigen or antibody) through use of...
by Joe Chaffin | Mar 10, 2016
Glossary Circular of Information Under Title 21 of the Code of Federal Regulations, blood and blood products must be “labeled” with appropriate information regarding uses, dosage, and administration instructions (just like the FDA requires for package...
by Joe Chaffin | Mar 10, 2016
Glossary Clinically Significant A term used to describe the fact that a particular blood group antibody can cause one of two problems: Hemolytic transfusion reactions Hemolytic disease of the fetus/newborn (HDFN) Most significant antibodies are IgG antibodies rather...
by Joe Chaffin | Mar 10, 2016
Glossary CLIA CLIA is an acronym for the “Clinical Laboratory Improvement Amendments,” a set of quality regulations that must be followed in every clinical laboratory in the U.S. The regulations cover all administrative aspects of running a clinical lab,...
by Joe Chaffin | Mar 11, 2016
Glossary Cold Antibody Any red cell antibody that binds its target antigen best at levels below body temperature (37 C) is commonly referred to as a “cold antibody” (this, of course, contrasts to “warm” antibodies that react best at or near...
