Glossary: Clinically Significant

Glossary Clinically Significant A term used to describe the fact that a particular blood group antibody can cause one of two problems: Hemolytic transfusion reactions Hemolytic disease of the fetus/newborn (HDFN) Most significant antibodies are IgG antibodies rather...

Glossary: CLIA

Glossary CLIA CLIA is an acronym for the “Clinical Laboratory Improvement Amendments,” a set of quality regulations that must be followed in every clinical laboratory in the U.S. The regulations cover all administrative aspects of running a clinical lab,...

Glossary: Cold Antibody

Glossary Cold Antibody Any red cell antibody that binds its target antigen best at levels below body temperature (37 C) is commonly referred to as a “cold antibody” (this, of course, contrasts to “warm” antibodies that react best at or near...

Glossary: Closed System

Glossary Closed System A closed system, in blood banking, is a blood container or collection process in which the sterility of a blood product is not compromised. We often use the phrase when a product is manipulated using equipment that allows the product to remain...

Glossary: Code of Federal Regulations

Glossary Code of Federal Regulations (CFR) The CFR is a gargantuan encyclopedia, 50 titles in length, with United States government regulations on everything from energy and the postal service all the way to domestic security and national defense. In the blood bank,...

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