by Joe Chaffin | Mar 9, 2016
Glossary Chemiluminescent Immunoassay Abbreviated “ChLIA,” this is a testing method used in blood donor infectious disease screening. ChLIA is very similar in concept to enzyme immunoassay (EIA) in both bind a substance (antigen or antibody) through use of...
by Joe Chaffin | Mar 10, 2016
Glossary Clinically Significant A term used to describe the fact that a particular blood group antibody can cause one of two problems: Hemolytic transfusion reactions Hemolytic disease of the fetus/newborn (HDFN) Most significant antibodies are IgG antibodies rather...
by Joe Chaffin | Mar 10, 2016
Glossary CLIA CLIA is an acronym for the “Clinical Laboratory Improvement Amendments,” a set of quality regulations that must be followed in every clinical laboratory in the U.S. The regulations cover all administrative aspects of running a clinical lab,...
by Joe Chaffin | Mar 11, 2016
Glossary Cold Antibody Any red cell antibody that binds its target antigen best at levels below body temperature (37 C) is commonly referred to as a “cold antibody” (this, of course, contrasts to “warm” antibodies that react best at or near...
by Joe Chaffin | Mar 10, 2016
Glossary Closed System A closed system, in blood banking, is a blood container or collection process in which the sterility of a blood product is not compromised. We often use the phrase when a product is manipulated using equipment that allows the product to remain...
